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Medical disclaimer

This symptom checker is for informational screening guidance only and cannot replace professional medical advice. Always consult a healthcare provider for diagnosis and treatment.

Symptom to recommended screen

This table is educational screening guidance, not a diagnosis. Home kits are useful for some infections; active sores, pelvic pain with fever, and possible HIV exposure within 72 hours need a clinician.

What you noticedWhat to screen for
Unusual genital discharge or burning when you peeChlamydia and gonorrhea screen (urine or swab). Ask for throat or rectal sampling if those sites were exposed.
Frothy, yellow-green, or strong-smelling vaginal dischargeTrichomoniasis plus chlamydia/gonorrhea screen.
Painless sore or ulcer on genitals, anus, or mouthSyphilis blood screen, and a clinician swab of the sore while it is present.
Painful blisters or grouped soresClinician swab of the lesion for herpes. Routine herpes blood screening is not recommended.
Rash on palms or soles, or a widespread body rash after a possible exposureSyphilis blood screen, plus a core STI panel.
Flu-like illness 2–6 weeks after a possible exposureHIV antigen/RNA-capable test through a clinician; antibody-only home screens can still be negative this early.
Condomless sex or a partner with unknown STI status, no symptomsCore 4 screen: chlamydia, gonorrhea, syphilis, and HIV. Time the blood tests to the window period.
Shared needles, needlestick, or unsterile tattoo/piercingHepatitis B, hepatitis C, and HIV screening.
Visible nits or burrow-like itchy rash in close contactsVisual diagnosis by a pharmacist or clinician — not a lab kit.
Possible HIV exposure within 72 hoursPEP from a clinic, urgent care, or emergency department. A home screen cannot help in that window.

Common questions

Can a home STI screen diagnose an infection?
No. A home screen is educational guidance only. Only a laboratory test or a clinician can diagnose an infection. Confirm any reactive result with a licensed provider.
When is an STI screen reliable after sex?
Each infection has a window period. A negative result taken too early can be falsely reassuring. Use a timing guide and repeat screening if you tested inside the window.
Should I get a routine herpes blood test?
Routine herpes serology is not recommended for people without symptoms or a known exposure. Herpes is best identified by swabbing an active lesion.
What should I do after a possible HIV exposure in the last 72 hours?
Ask a clinic, urgent care, or emergency department about PEP (post-exposure prophylaxis) immediately. Do not wait for a home screen result.